Clinical Considerations and Biomarker Development
This course will cover fundamental concepts about the criteria for something to qualify as a biomarker and how they are analyzed by mass spectrometry from a variety of biological fluids and/or tissues. We will also discuss the broader uses of mass spectrometry in a clinical or hospital setting.
Prerequisites: Enrollment in CAMS-MS program.
Outcomes: At the end of this course students will be able to: 1) Compare and contrast aspects of good vs bad biomarkers and the utility of mass spectrometry for their detection in biological samples; 2) Describe best practices for sample collection and the limitations of using biological samples; 3) Describe current regulations and standards for biomarker use in the clinic; 4) Identify and describe biohazard safety issues when working with biological samples; 5) Describe analytical approaches for quantification of biomarkers; and 6) Describe the type of mass spectrometry assays typically used in a clinical or hospital setting.
Prerequisites: Enrollment in CAMS-MS program.
Outcomes: At the end of this course students will be able to: 1) Compare and contrast aspects of good vs bad biomarkers and the utility of mass spectrometry for their detection in biological samples; 2) Describe best practices for sample collection and the limitations of using biological samples; 3) Describe current regulations and standards for biomarker use in the clinic; 4) Identify and describe biohazard safety issues when working with biological samples; 5) Describe analytical approaches for quantification of biomarkers; and 6) Describe the type of mass spectrometry assays typically used in a clinical or hospital setting.