Chemistry of Protein Separation
This course will cover the fundamentals of separating biological agents in solution for analysis by mass spectrometry.
Prerequisite: Enrollment in CAMS-MS program.
Outcomes: At the end of this course students will be able to: 1) Describe the composition of typical biological collections including blood and waste; 2) Describe best-practices for preparing collections for mass spectrometry; 3) Describe fundamentals of separating biomolecules according to size, charge and other physiochemical factors; and 4) Describe mechanisms and tradeoffs behind common approaches for separating biological samples via chromatography (liquid and gas).
Prerequisite: Enrollment in CAMS-MS program.
Outcomes: At the end of this course students will be able to: 1) Describe the composition of typical biological collections including blood and waste; 2) Describe best-practices for preparing collections for mass spectrometry; 3) Describe fundamentals of separating biomolecules according to size, charge and other physiochemical factors; and 4) Describe mechanisms and tradeoffs behind common approaches for separating biological samples via chromatography (liquid and gas).