Medicinal Chemistry
This course explores how medicinal chemists design and synthesize new drug candidates as well as the hurdles that must be overcome in meeting the FDA requirements of efficacy and safety on the road to market, emphasizing the therapeutic index that underscores the risk/benefit consideration of every drug.
Outcomes: 1) Explain risk/benefit of drugs in efficacy vs. toxicity and the therapeutic index/window; 2) Summarize interactions of drugs with receptors, enzymes, or nucleotides; 3) Analyze structure-activity relationships given potency data.
Outcomes: 1) Explain risk/benefit of drugs in efficacy vs. toxicity and the therapeutic index/window; 2) Summarize interactions of drugs with receptors, enzymes, or nucleotides; 3) Analyze structure-activity relationships given potency data.