Fundamentals of Drug Discovery and Development
This course introduces the process of drug discovery, and students will explore the theoretical and practical aspects of the entire process from concept to clinical trials. Topics include selection, design and use of disease models, current methods and strategies of drug target identification, lead molecule identification, the clinical trial process and pre- and post-market safety.
Outcomes: Upon completion of this course, the students will have sufficient understanding of the drug discovery process to: 1) Discuss the methods and strategies used to identify potential drug targets; 2) Describe approaches used to screen for lead molecules; 3) Articulate the general FDA regulatory requirements encountered in bringing a new drug to market; 4) Identify requirements for pre-clinical assessment of potential compounds; 5) Define and describe the steps of the clinical trials process; and 6) Articulate and discuss ethical aspects in drug development, including, but not limited to, animal use, clinical trials, intellectual property and research design and integrity.
Outcomes: Upon completion of this course, the students will have sufficient understanding of the drug discovery process to: 1) Discuss the methods and strategies used to identify potential drug targets; 2) Describe approaches used to screen for lead molecules; 3) Articulate the general FDA regulatory requirements encountered in bringing a new drug to market; 4) Identify requirements for pre-clinical assessment of potential compounds; 5) Define and describe the steps of the clinical trials process; and 6) Articulate and discuss ethical aspects in drug development, including, but not limited to, animal use, clinical trials, intellectual property and research design and integrity.